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CVE-2026-100843

Project-monai Monai remote code execution

7.8 HIGHPublic exploitEPSS 0.20%
  1. Published27 Sept 2026

Description

MONAI versions before 1.6.0 contain a remote code execution vulnerability in the algo_from_pickle() function due to unsafe pickle.loads() deserialization in monai/auto3dseg/utils.py. Attackers can craft malicious pickle files that execute arbitrary system commands when deserialized by the vulnerable function.

CVSS 3.1 breakdown

Attack vectorLocal
Attack complexityLow
Privileges requiredNone
User interactionRequired
ScopeUnchanged
ConfidentialityHigh
IntegrityHigh
AvailabilityHigh
CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H

Affected products

Project-monai Monai< 1.6.0

Remediation

Fixed in
Project-monai Monai≥ 1.6.0

References

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Frequently asked

Is CVE-2026-100843 being actively exploited?

CVE-2026-100843 is not in the CISA KEV catalog. A public exploit reference exists, so treat it as exploitable. Its EPSS exploit probability is 0.20%.

How severe is CVE-2026-100843?

CVE-2026-100843 has a CVSS 3.1 base score of 7.8, rated high. EPSS estimates a 0.20% probability of exploitation.

Which products are affected by CVE-2026-100843?

Affected products include Project-monai Monai.

How do I fix CVE-2026-100843?

Upgrade affected software to a fixed version, for example Project-monai Monai 1.6.0 or later, then confirm no affected versions remain in your inventory.

How Secuno handles this

Secuno correlates vulnerabilities like CVE-2026-100843 against the real software inventory on every managed device, as each hourly inventory arrives. Rather than a static severity, each match is scored in context: exploit availability, EPSS, the asset's exposure, and business criticality decide where it lands in the queue. If an affected version is present anywhere across your portfolio, it surfaces automatically with a prioritised remediation path.

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Data from the NVD, CISA KEV catalog and FIRST EPSS. CVSS 3.1 base score shown where available.