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CVE-2026-100845

Project-monai Monai insecure deserialization

7.8 HIGHPublic exploitEPSS 0.14%
  1. Published27 Sept 2026

Description

MONAI before 1.6.0 contains an unsafe deserialization vulnerability in the NumpyReader class that unconditionally uses numpy.load with allow_pickle=True when loading .npy and .npz files. Attackers can craft malicious .npy files with pickle payloads that execute arbitrary code when loaded through MONAI's standard data pipeline.

CVSS 3.1 breakdown

Attack vectorLocal
Attack complexityLow
Privileges requiredNone
User interactionRequired
ScopeUnchanged
ConfidentialityHigh
IntegrityHigh
AvailabilityHigh
CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H

Affected products

Project-monai Monai< 1.6.0

Remediation

Fixed in
Project-monai Monai≥ 1.6.0

References

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Frequently asked

Is CVE-2026-100845 being actively exploited?

CVE-2026-100845 is not in the CISA KEV catalog. A public exploit reference exists, so treat it as exploitable. Its EPSS exploit probability is 0.14%.

How severe is CVE-2026-100845?

CVE-2026-100845 has a CVSS 3.1 base score of 7.8, rated high. EPSS estimates a 0.14% probability of exploitation.

Which products are affected by CVE-2026-100845?

Affected products include Project-monai Monai.

How do I fix CVE-2026-100845?

Upgrade affected software to a fixed version, for example Project-monai Monai 1.6.0 or later, then confirm no affected versions remain in your inventory.

How Secuno handles this

Secuno correlates vulnerabilities like CVE-2026-100845 against the real software inventory on every managed device, as each hourly inventory arrives. Rather than a static severity, each match is scored in context: exploit availability, EPSS, the asset's exposure, and business criticality decide where it lands in the queue. If an affected version is present anywhere across your portfolio, it surfaces automatically with a prioritised remediation path.

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Data from the NVD, CISA KEV catalog and FIRST EPSS. CVSS 3.1 base score shown where available.