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CVE-2026-100846

Project-monai Monai insecure deserialization

7.6 HIGHPublic exploitEPSS 0.29%
  1. Published27 Sept 2026

Description

MONAI before 1.5.2 contains a deserialization of untrusted data vulnerability in the algo_from_pickle function in monai/auto3dseg/utils.py. The function reads a .pkl file and passes its contents to pickle.loads without validating the data source or content. If an application invokes algo_from_pickle on an attacker-supplied pickle file, an object defining __reduce__ is executed during deserialization, resulting in arbitrary code execution in the context of the application.

CVSS 3.1 breakdown

Attack vectorNetwork
Attack complexityHigh
Privileges requiredHigh
User interactionRequired
ScopeChanged
ConfidentialityHigh
IntegrityHigh
AvailabilityHigh
CVSS:3.1/AV:N/AC:H/PR:H/UI:R/S:C/C:H/I:H/A:H

Affected products

Project-monai Monai< 1.5.2

Remediation

Fixed in
Project-monai Monai≥ 1.5.2

References

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Frequently asked

Is CVE-2026-100846 being actively exploited?

CVE-2026-100846 is not in the CISA KEV catalog. A public exploit reference exists, so treat it as exploitable. Its EPSS exploit probability is 0.29%.

How severe is CVE-2026-100846?

CVE-2026-100846 has a CVSS 3.1 base score of 7.6, rated high. EPSS estimates a 0.29% probability of exploitation.

Which products are affected by CVE-2026-100846?

Affected products include Project-monai Monai.

How do I fix CVE-2026-100846?

Upgrade affected software to a fixed version, for example Project-monai Monai 1.5.2 or later, then confirm no affected versions remain in your inventory.

How Secuno handles this

Secuno correlates vulnerabilities like CVE-2026-100846 against the real software inventory on every managed device, as each hourly inventory arrives. Rather than a static severity, each match is scored in context: exploit availability, EPSS, the asset's exposure, and business criticality decide where it lands in the queue. If an affected version is present anywhere across your portfolio, it surfaces automatically with a prioritised remediation path.

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Data from the NVD, CISA KEV catalog and FIRST EPSS. CVSS 3.1 base score shown where available.